Job Title: HEVA (Health Economics & Value Assessment) Business Partner -Multiple Myeloma
Location: Cambridge, MA, hybrid
Job type: Permanent, Full time
Sanofi Specialty Care has pioneered the development and delivery of transformative therapies for patients affected by debilitating diseases for over 30 years. We accomplish our goals through world-class research, collaboration with the global patient community, and with the compassion and commitment of our employees. With a focus on rare diseases, multiple sclerosis and onco-immunology, we are dedicated to making a positive impact on the lives of the patients and families we serve. Sanofi Specialty Care’s portfolio of transformative therapies, which are marketed in countries around the world, represent ground-breaking and life-saving advances in medicine. Sanofi Specialty Care employees benefit from the reach and resources of one of the world's largest pharmaceutical companies with a shared commitment to improving the lives of patients.
Sanofi’s Oncology franchise has a diverse and fast-growing portfolio. This includes late-stage launching candidates in multiple myeloma and lung cancer as well as several promising compounds in the pipeline targeting hematologic malignancies and solid tumors alike. Sarclisa is approved for relapsed refractory multiple myeloma (RRMM) and is currently being explored in newly diagnosed multiple myeloma patients. HEVA’s mission is to conduct, communicate, and translate evidence to demonstrate the value of Sanofi’s products and support optimal access and treatment outcomes for patients. The oncology HEVA team is responsible for designing and fulfilling evidence generation plans that meet the strategic goals of oncology portfolio.
The HEOR/HEVA business partner in this position will support Sarclisa upcoming global launches and pipeline indications in collaboration with the cross functional teams.
This role will be responsible for development of Health Economic and Outcomes Research (HEOR) strategy and execution of relevant tactics to support the value proposition of Sarclisa for multiple myeloma indications. The incumbent will interface with market access, Clinical, Medical Affairs, and commercial teams including Global and US. The role is accountable for the planning, design, implementation, and completion of innovative evidence-based research programs that are consistent with program/product strategies. The research programs will provide appropriate evidence and/or tools to be used for internal decision making and for external audiences at product launch and over product life cycle.
This role will be responsible for the design and execution of Health Economic and Outcomes Research (HEOR) research in the forms of economic modeling, database analysis, observational research, Clinical Outcomes Assessment (COA) development and validation, systematic literature review, evidence synthesis, value dossier development and other types of HEOR research, and provide trial design recommendations.
This role will set the HEOR evidence generation priorities and plan for the assigned oncology indications in life cycle or under development and incorporate them into broader Sanofi planning documents such as the integrated evidence generation plan (IEGP).
This role will operate as part of a multi-functional global Brand team and development team that is responsible for designing clinical research programs to meet the evidentiary standards of regulators, health technology assessment (HTA) organizations, reimbursement authorities, third-party payers and other organizations that review evidence relevant to Sanofi medicines.
This role will serve as a subject matter expert to provide input in various commercial, medical, market access teams, and strategy development
This role is expected to demonstrate effective communication, organizational and interpersonal skills to be able to work effectively as part of a multidisciplinary team. The incumbent is expected to work independently, but in concert with the direction provided by their management, in accordance with defined functional policies and precedents, budgetary guidelines, company values, ethics and applicable law.
Market Access & Pricing, Global, US and x-US affiliates
Cross functional Brand team
Medical Affairs - GBUs, affiliates, HEVA RW Evidence and Analytics, Clinical Outcomes Generation
R&D – Global project teams and Clinical Affairs, Clinical Outcomes Assessment (COA) and Health Value Translation (HVT)
Public Affairs, Communications
Regulatory Affairs, Compliance and Legal
Key Opinion Leaders (KOLs)
Health Technology Assessment (HTAs) and other review bodies
Key Performance Indicators:
Timely design and execution of the HEVA plan
Demonstrated contributions to product success
Development and execution of strategies that address data gaps and customer needs
Expertise recognized within the function
Develops and maintains peer relationships to establish HEVA as an expert in HEOR.
Anticipates communication needs to cross-functional audiences and pre-empts issues with timely and effective action
Established track record of scientific and/or methods publications in peer-reviewed journals
Compliance with all relevant internal SOPs and external laws and regulations.
Advanced degree (PhD, MD, MS, MPH, or PharmD) in a scientific discipline
Minimum of 5-7 years of combined experience in health economics, outcomes research, or a related field
Demonstrated experience in applying various HEOR methods to specific research projects and have supported global launches.
Previous experience in oncology
Proficiency in principles of evidence-based medicine and clinical research methodology, economic modeling, and COAs.
Understands, creates, and applies relevant methods (e.g., observational data, post hoc analysis of clinical trials, meta-analysis, indirect comparison, etc..) to demonstrate product value potential
Provided recommendations to clinical development programs aimed at ensuring differentiation for payer value demonstration
Has experience in translating Target Value Propositions and access strategies into evidence hypotheses, requirements and generation plans addressing payer/provider/health system unmet needs
Publication in peer-reviewed journals
Knowledge of global HTA processes and guidelines, experience with HTA submissions preferred
Knowledge of US payers and guidelines, experience with US submissions preferred
Strong ability to partner with colleagues from other (i.e. non-HEOR) functional areas
Demonstrated understanding disease physiopathology, drug mechanism of action, clinical development principles, epidemiology, biostatistics, statistical programming COA development, systemic literature reviews, and network meta-analyses
Skills & Competencies:
English fluent, both written and oral
Strong communication skills, both verbal and written, including presentation skills. Significant experience making presentations to senior management is strongly desired
Understanding of the legal and regulatory environment of the pharmaceutical industry, demonstrated integrity on work-related compliance considerations and solid ethics
Entrepreneurial and team spirit and ability to develop creative solutions to complex problems
Pursue progress, discover extraordinary!
Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity.
Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!
As a healthcare company and a vaccine manufacturer, Sanofi has an important responsibility to protect individual and public health. All US based roles require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities.
According to the CDC, an individual is considered to be “fully vaccinated” fourteen (14) days after receiving (a) the second dose of the Moderna or Pfizer vaccine, or (b) the single dose of the J&J vaccine. Fully vaccinated, for new Sanofi employees, is to be fully vaccinated 14 DAYS PRIOR TO START DATE.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.