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Head of Immuno-Oncology Cell Therapy Cluster

date posted 07/21/2020
contract type Full time
job id R2560407
location Cambridge, Massachusetts

Head of Immuno-Oncology Cell Therapy Cluster– Cambridge, USA, Immuno-Oncology Research Therapeutic Area

Sanofi is expanding its pipeline and capabilities in immuno-oncology and is seeking outstanding scientists with significant experience in immunology, immuno-oncology and cell therapy to help further develop safe and effective medicines for cancer patients.

Job Responsibilities/Department Description:

As a Head of the Immuno-Oncology Cell Therapy Cluster based in Cambridge, USA, you will develop and advance cutting-edge therapeutics by driving scientific innovation, excellence and rigor. The Head of Immuno-Oncology Cell Therapy Cluster will manage a team of scientists based in Cambridge and will also lead research teams supported by multidisciplinary platforms and scientists based in the Boston area and around the globe.  The Cluster Head will identify and validate new universal cell therapy modalities working with experts within and outside their team using a variety of tools, including human immunology, human genetics, human sample analyses, bioinformatics, clinical data, and preclinical in vitro and in vivo models.

The Head of Immuno-Oncology Cell Therapy Cluster will work closely with research and development colleagues to ensure the progression of projects from concept to clinical testing, focusing on developing and validating impactful cell therapy approaches with a strong translational rationale.  The Cluster Head will maintain a leadership position in cancer research communities, connecting Sanofi scientists with collaborators around the globe. The Cluster Head Director will establish and manage productive collaborations with external scientists to help drive innovation. The Head of Immuno-Oncology Cell Therapy Cluster will work closely with the Global Head of the Immuno-Oncology Research Therapeutic Area to develop and integrate a research strategy for the entire Immuno-Oncology Research Therapeutic Area, coordinate and contribute to portfolio review and prioritization, and will be part of the Immuno-Oncology Leadership Team, together with other senior leaders and key business partners.  In addition, the Head of Immuno-Oncology Cluster in Cambridge, USA is expected to forge close collaboration with the Heads of Immuno-Oncology Clusters in Vitry, France, to leverage mutual capabilities and expertise at both research sites and promote cross-site exchanges.  

Key Accountabilities:

  • Lead a Cluster/Department of scientists responsible for identifying novel universal cell therapy modalities and associated targets and combinations in anti-cancer immunity; connecting cutting-edge science with unmet medical need.
  • Support the Immuno-Oncology Research Therapeutic Area strategy by identifying new universal cell therapy modalities and advancing projects in the current pipeline.  Lead scientists experienced in a range of disciplines, from molecular and cell biology, immunology, genetics, genome editing and pharmacology, to develop deep mechanistic understanding of disease pathogenesis and confidence in cell therapy rationale
  • Lead internally and externally in an area of immuno-oncology research, publishing cutting edge science and developing and maintaining key collaborations around the globe. 
  • Actively seek and promote scientific collaboration opportunities between Immuno-Oncology and Molecular Oncology Research Therapeutic Areas, whenever feasible
  • Manage collaborative relationships with project leads, key internal and external stakeholders, especially CMC, and with the Sanofi research platform leadership to resource and advance portfolio projects
  • Recruit, retain and develop world-class scientific talent

Essential Qualifications:

  • PhD or MD/PhD with postdoctoral and/or fellowship training.  12+ years of experience developing and leading research programs, including experience in cell therapy.  12+ years of experience in drug discovery and development or equivalent academic experience preferred.

Preferred Qualifications:

  • Deep expertise and outstanding record of research and publications in immunology, immuno-oncology, cell therapy and cancer biology. 
  • Expertise in extending discovery research through translational human biology to clinical development, using human biology approaches, biomarker development and validation, and forward and back translation of research and clinical endpoints.
  • Experience leading multi-disciplinary, matrixed teams.
  • Understanding of complex research landscapes globally, ability to identify cutting-edge research and new directions, and connect internal and external colleague productively.
  • Outstanding management, communication and interpersonal skills.
  • Experience with multi-cultural teams and environments.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

The successful candidate will be required to sign and execute a restricted covenant upon hire.

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At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

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