The Cell Biology Team in the In Vitro Biology Department of Sanofi-Genzyme’s Integrated Drug Discovery Platform is seeking an experienced and highly-motivated Principal Scientist. The job entails supporting early drug discovery projects by testing small molecule candidates in various cellular models and assays. A thorough understanding of the drug discovery process is required. The successful candidate should be able to establish cellular models to support multiple therapeutic areas as well as characterize these models for target/disease relevance. As an active, enthusiastic member of project teams, the candidate will work collaboratively with medicinal chemists, biologists, pharmaceutical scientists and must be able to present scientific results at team meetings. With an appropriate sense of urgency, the successful candidate will bring valuable experiences to address scientific questions with new methods and processes.
The successful candidate will have a Ph.D. with 3-5 years of professional experience developing in vitro assays in the biotech/pharmaceutical environment. Experience working on early-stage drug discovery project teams is required.
The job requires extensive experience developing and validating in vitro cellular screens, backed by solid technical skills in cellular characterization and target probing techniques (CRISPER, siRNA modulation..).
Knowledge of high-content screening is a plus, as is familiarity with derivation, differentiation, maintenance of iPSC’s.
The successful candidate will become a resource across the IVB platform and must possess both management experience and demonstrate mentoring abilities in addition to excellent writing and presentation skills.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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